SHBG, sex hormone binding globulin, 6462

N. diseases: 368; N. variants: 20
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0221155
Disease: Systolic hypertension
Systolic hypertension
0.060 Biomarker disease BEFREE Patients with poorly controlled hypertension (systolic blood pressure [SBP] ≥130 mmHg and/or diastolic blood pressure [DBP] ≥80 mmHg) at study initiation were extracted to investigate the effect of teneligliptin on blood pressure. 30974980 2020
CUI: C0221155
Disease: Systolic hypertension
Systolic hypertension
0.060 Biomarker disease BEFREE <b>Results:</b> SU induces hypertension (systolic blood pressure [SBP] + 28.33 ± 5.00 mmHg) and left ventricular dysfunction (left ventricular ejection fraction [LVEF] - 11.16 ± 2.53%) in mice. 31545912 2019
CUI: C0221155
Disease: Systolic hypertension
Systolic hypertension
0.060 Biomarker disease BEFREE To test whether elevated blood pressure (BP) relates to gray matter (GM) volume (GMV) changes in young adults who had not previously been diagnosed with hypertension (systolic BP [SBP]/diastolic BP [DBP] ≥140/90 mm Hg). 30674602 2019
CUI: C0221155
Disease: Systolic hypertension
Systolic hypertension
0.060 Biomarker disease BEFREE The primary endpoint was new-onset hypertension (systolic blood pressure [SBP]/diastolic blood pressure [DBP] ≥ 140/90 mm Hg and/or the initiation of antihypertensive medications with self-reported hypertension). 29604170 2018
CUI: C0221155
Disease: Systolic hypertension
Systolic hypertension
0.060 Biomarker disease BEFREE The echocardiographic parameters of diastolic function were compared between patients who had postoperative BP abnormalities (hypertension-systolic blood pressure [SBP] ≥ 170 mmHg-or hypotension-SBP < 80 mmHg-episode) that required therapeutic interventions until 7 days after surgery and those who had no BP abnormalities. 30369572 2018
CUI: C0221155
Disease: Systolic hypertension
Systolic hypertension
0.060 Biomarker disease BEFREE The primary end point was new-onset hypertension (systolic BP [SBP]/diastolic BP [DBP] ≥140/90 mm Hg and/or the initiation of antihypertensive medications with self-reported hypertension). 28444926 2017