Diabetes
|
0.020 |
Biomarker
|
disease |
BEFREE |
We demonstrate upregulation of the Knot ortholog EBF2 in glomeruli of human diabetic nephropathy patients and a mouse ob/ob diabetes model.
|
26190114 |
2015 |
Diabetes Mellitus
|
0.020 |
Biomarker
|
group |
BEFREE |
We demonstrate upregulation of the Knot ortholog EBF2 in glomeruli of human diabetic nephropathy patients and a mouse ob/ob diabetes model.
|
26190114 |
2015 |
Metastatic osteosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results provided new therapeutic targets for metastatic osteosarcoma and insights into molecular regulation of EBF2.
|
30529043 |
2019 |
Tumor Cell Invasion
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Besides, our data further revealed that overexpressed EBF2 inhibited apoptosis and facilitated migration and invasion of osteosarcoma cells.
|
30529043 |
2019 |
Lupus Erythematosus, Systemic
|
0.010 |
Biomarker
|
disease |
BEFREE |
There was a weak association between anti-EBF2 and SLE disease activity but no significant associations were determined for other measured IgG reactivity.
|
30041579 |
2018 |
Mucocutaneous Lymph Node Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The present study investigated the association between KD and single nucleotide polymorphisms (SNPs) in the candidate gene early B cell factor 2 (EBF2), which is associated with inflammation markers.
|
29749135 |
2018 |
Anorectal Malformations
|
0.010 |
GeneticVariation
|
group |
BEFREE |
These results support that missense mutation in the EBF2 c.215C > T (p.Ala72Val) is very likely to contribute to the pathogenesis of ARM in this family.
|
29704291 |
2018 |
Obesity
|
0.010 |
Biomarker
|
disease |
BEFREE |
Overall, the study highlights the existence of novel regulatory mechanisms between Id1/PGC1α and Id1/Ebf2 in controlling brown fat metabolism, which has significant implications in the treatment of obesity and its associated diseases, such as diabetes.
|
28270523 |
2017 |
Peripheral Neuropathy
|
0.010 |
Biomarker
|
group |
BEFREE |
To get insight into Ebf2 function in peripheral nervous system, here we characterize the peripheral neuropathy affecting these mice.
|
21220016 |
2011 |
Peripheral motor neuropathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Both Schwann cell and axonal defects cause motor peripheral neuropathy in Ebf2-/- mice.
|
21220016 |
2011 |
Peripheral Nervous System Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
To get insight into Ebf2 function in peripheral nervous system, here we characterize the peripheral neuropathy affecting these mice.
|
21220016 |
2011 |
Blast Phase
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
In chronic myeloid leukemia (CML) two of the genes, (TFAP2A and EBF2), demonstrated increased methylation in blast crisis compared to chronic phase (P < 0.05).
|
20184741 |
2010 |
Myeloid Leukemia, Chronic
|
0.010 |
Biomarker
|
disease |
BEFREE |
In chronic myeloid leukemia (CML) two of the genes, (TFAP2A and EBF2), demonstrated increased methylation in blast crisis compared to chronic phase (P < 0.05).
|
20184741 |
2010 |
Kallmann Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Nasal embryonic LHRH factor (NELF) and early B-cell factor 2 (EBF2) exons were evaluated in KAL-1/GnRH-R mutation-negative cases (seven KS and five nHH) by sequence analysis but no mutations were identified in the coding regions in these patients.
|
16423815 |
2005 |