Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE cAMP-responsive element-binding protein (CREB)-regulated transcriptional coactivator 3 (CRTC3) is well known to be related to obesity in humans and mice. 29220752 2018
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE Previous studies show that global knockout of CRTC3 enhances oxygen consumption and energy expenditure and subsequently protects the knockout animal against obesity. 28322447 2018
CUI: C0028754
Disease: Obesity
Obesity
0.040 GeneticVariation disease BEFREE So we investigated whether the polymorphisms of CRTC3 could confer risks of obesity or other metabolic disorders in Chinese population. 24264430 2014
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE As a common human CRTC3 variant with increased transcriptional activity is associated with adiposity in two distinct Mexican-American cohorts, these results suggest that adipocyte CRTC3 may play a role in the development of obesity in humans. 21164481 2010