Disease: Brain Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.060 AlteredExpression group BEFREE Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells. 31115870 2019
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.060 AlteredExpression group BEFREE Increased expression of the Bmi-1 in pediatric brain tumors may be important in the acquisition of an aggressive phenotype. 23984324 2013
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.060 Biomarker group BEFREE Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells. 22265735 2012
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.060 Biomarker group BEFREE Stable BMI1 knockdown using short hairpin RNA-expressing lentiviruses resulted in inhibition of clonogenic potential in vitro and of brain tumor formation in vivo. 19605626 2009
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.060 Biomarker group BEFREE This data suggests that BMI1 gene is aberrant at the chromosomal level in a subset of gliomas, and possibly contributes to brain tumour pathogenesis. 18427816 2008
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.060 Biomarker group BEFREE In this issue of Cancer Cell, Bruggeman and colleagues suggest that brain tumors with these molecular alterations can be initiated in both neural precursor and differentiated cell compartments in the absence of Bmi1; however, tumorigenicity is reduced, and tumors contain fewer precursor cells. 17936553 2007