Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.020 GeneticVariation disease BEFREE We determined rs2284749 in the ST6GAL1 gene that was associated with a decreased risk of lung cancer in the Chinese Han population, based on the recessive model (odds ratio: 0.66; 95% confidence interval: 0.44-0.99, P = 0.045). 31794515 2020
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.020 Biomarker disease BEFREE Modification of α2,6-sialylation positively associates with lung cancer progression, thereby indicating that ST6Gal-I may mediate the invasiveness and tumorigenicity of NSCLC cells via the Notch1/Hes1/MMPs pathway both in vitro and in vivo. 29981167 2018