|
Bipolar Disorder
|
0.310 |
Biomarker
|
disease |
BEFREE |
These findings with ADCY8 and ST3GAL1 warrant further investigation in order to confirm the observed associations and their functional significance for BP susceptibility.
|
18163389 |
2008 |
|
Bipolar Disorder
|
0.310 |
Biomarker
|
disease |
PSYGENET |
These findings with ADCY8 and ST3GAL1 warrant further investigation in order to confirm the observed associations and their functional significance for BP susceptibility.
|
18163389 |
2008 |
|
Psychotic Disorders
|
0.310 |
Biomarker
|
group |
PSYGENET |
In a secondary analysis of these 6 genes among parent-proband trios with a history of psychosis, evidence of the association with SIAT4A was strengthened.
|
18180429 |
2008 |
|
Psychotic Disorders
|
0.310 |
Biomarker
|
group |
BEFREE |
In a secondary analysis of these 6 genes among parent-proband trios with a history of psychosis, evidence of the association with SIAT4A was strengthened.
|
18180429 |
2008 |
|
Nonorganic psychosis
|
0.310 |
Biomarker
|
disease |
PSYGENET |
In a secondary analysis of these 6 genes among parent-proband trios with a history of psychosis, evidence of the association with SIAT4A was strengthened.
|
18180429 |
2008 |
|
Nonorganic psychosis
|
0.310 |
Biomarker
|
disease |
BEFREE |
In a secondary analysis of these 6 genes among parent-proband trios with a history of psychosis, evidence of the association with SIAT4A was strengthened.
|
18180429 |
2008 |
|
Enterovirus Infections
|
0.300 |
Biomarker
|
group |
CTD_human |
CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection.
|
28446605 |
2017 |
|
Schizophrenia
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Family-based association study of lithium-related and other candidate genes in bipolar disorder.
|
18180429 |
2008 |
|
Postmenopausal frontal fibrosing alopecia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.
|
30850646 |
2019 |
|
Frontal fibrosing alopecia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.
|
30850646 |
2019 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
Breast Carcinoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Examination of 114 fresh primary breast cancer and their adjacent normal tissues showed that the expression levels of ST3Gal1 and TGFB1 were high in tumor part and the expression of two genes was positively correlated.
|
30252131 |
2019 |
|
Breast Carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Silencing ST3GAL1 in breast cancer cells reduced GDNF-induced phosphorylation of RET, AKT and ERα, as well as GDNF-mediated cell proliferation.
|
30040982 |
2018 |
|
Breast Carcinoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Induction of COX-2 in the MDA-MB-231 breast cancer cell line also results in the increased expression of ST3Gal-I, leading to increased sialylation of the substrate of ST3Gal-I, core 1 Galβ1,3GalNAc.
|
23275522 |
2012 |
|
Breast Carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
These results indicate that ST3Gal-I is acting as a tumor promoter in this model of breast cancer.
|
20534593 |
2010 |
|
Breast Carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Thus, the aberrant glycosylation of MUC1 seen in breast carcinomas appears to be due, at least in part, to the elevation of ST3Gal I.
|
10561455 |
1999 |
|
Malignant neoplasm of breast
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Examination of 114 fresh primary breast cancer and their adjacent normal tissues showed that the expression levels of ST3Gal1 and TGFB1 were high in tumor part and the expression of two genes was positively correlated.
|
30252131 |
2019 |
|
Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Examination of 114 fresh primary breast cancer and their adjacent normal tissues showed that the expression levels of ST3Gal1 and TGFB1 were high in tumor part and the expression of two genes was positively correlated.
|
30252131 |
2019 |
|
Malignant neoplasm of breast
|
0.040 |
Biomarker
|
disease |
BEFREE |
Moreover, GDNF induced transcription of ST3GAL1, revealing a positive feedback loop regulating ST3GAL1 and GDNF/GFRA1/RET signaling in breast cancers.
|
30040982 |
2018 |
|
Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Moreover, high expression of ST3GAL1 was associated with poor clinical outcome in patients with late stage breast cancer and high expression of both ST3GAL1 and GFRA1 adversely impacted outcome in those with high grade tumors.
|
30040982 |
2018 |
|
Malignant neoplasm of breast
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Induction of COX-2 in the MDA-MB-231 breast cancer cell line also results in the increased expression of ST3Gal-I, leading to increased sialylation of the substrate of ST3Gal-I, core 1 Galβ1,3GalNAc.
|
23275522 |
2012 |
|
Malignant neoplasm of breast
|
0.040 |
Biomarker
|
disease |
BEFREE |
These results indicate that ST3Gal-I is acting as a tumor promoter in this model of breast cancer.
|
20534593 |
2010 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
These results indicate that ST3Gal-I is acting as a tumor promoter in this model of breast cancer.
|
20534593 |
2010 |
|
Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Furthermore, the level of mRNA expression encoding ST3Gal I is correlated to the intensity of staining seen with the antibody SM3, which specifically recognises underglycosylated, tumour associated MUC1.
|
10561455 |
1999 |