|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Results:</b> Our results showed that CaD was capable of reducing albuminuria and restoring renal histological changes in KK-Ay and HFD/STZ-induced diabetic mice.
|
31447680 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Diabetes was induced by 5 weeks feeding of Wistar rats with high fat diet (HFD) and subsequent i.p injection of STZ (35 mg/kg).
|
31089371 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
PRACTICAL APPLICATIONS: Owing to the effectiveness of Momordica Charantia extracts in management of diabetes in STZ-induced diabetic rats, we have intention to evaluate the powder of Charantia to discover novel drug for treating diabetes.
|
31441956 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Streptozotocin-induced type 1 (STZ 75 mg/Kg) diabetes inhibited the responsiveness of C-fibers nociceptors located in the TMJ of Wistar rats since seventh day after the disease induction.
|
31404587 |
2019 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Additionally, both L-aptamers significantly attenuated diabetes progression in the MLD-STZ model.
|
31267721 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
We introduced permanent middle cerebral artery occlusion (pMCAO) in a model of type 2 diabetic rats prepared by high-fat diet combined with intraperitoneal injection of STZ in vivo and mimicked cerebral ischemia with diabetes by employing high glucose stimulation and oxygen-glucose deprivation/reoxygenation (OGD/R) in vitro.
|
31082455 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
The induction of diabetes was performed using a single intraperitoneal (IP) injection of STZ (50 mg/kg).
|
30597310 |
2019 |
|
Diabetes
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We investigated two levels of STZ- induced diabetes: long-term mild diabetes (blood glucose level: 120-200 mg/dL) and short-term severe diabetes (blood glucose level >300 mg/dL).
|
29513796 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Nine week-old SS rats were treated with (STZ; 50 mg/kg ip) to induce diabetes.
|
29846112 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rats were injected with STZ (50 mg/kg, ip) to induce diabetes.
|
30150789 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we evaluated the effects of Andro against diabetes-induced myocardial dysfunction and explored the underlying mechanism in STZ-induced diabetic mice.
|
30046380 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Antidiabetic activity of mefloquine via GLP-1 receptor modulation against STZ-NA-induced diabetes in albino wistar rats.
|
29744272 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Increased gene expression level of GLP-1 receptor and NGF may underlie the beneficial action of exenatide in STZ/NA-induced diabetes.
|
29091313 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
A single injection of STZ (70 mg/kg; i.p.) was injected to male albino Wistar rats to induce diabetes.
|
28181586 |
2017 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Group I, Normal control; Group II, STZ diabetic; Group III and IV, Momordica charantia fruit juice was orally administered to diabetic rats (10 mL/kg/day either as prophylaxis for 14 days before induction of diabetes then 21 days treatment, or as treatment given for 21 days after induction of diabetes).
|
28064559 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Using STZ induced diabetes in rat as a model, we measured redox-imbalance related parameters including aldose reductase activity, level of poly ADP ribose polymerase (PAPR-1), NAD<sup>+</sup> content, NADPH content, reduced form of glutathione (GSH), and glucose 6-phophate dehydrogenase (G6PD) activity.
|
27888691 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
We found that IL-20 and its receptor IL-20R1 were upregulated in the kidneys of mice and rats with STZ-induced diabetes.
|
28360429 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Diabetes was induced by single intraperitoneal (i.p.) injection of STZ (50mg/kg/b.w.) and NA (110mg/kg/b.w.).
|
28549291 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Swiss mice, Mus musculus, were subjected to fluoride toxicity by providing fluoride-supplemented drinking water (600 ppm NaF) for a period of 30 days after the confirmation of streptozotocin-induced diabetes(STZ, 50 mg/kgbw).
|
27854046 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
In a subsequent series of experiments, OVX rats received high-fat diet and low dose STZ to induce diabetes (OVX.D) and genistein treatment (OVX.D.G).
|
29085595 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
We examined these mice and wild type littermate controls with or without STZ induced diabetes.
|
28279663 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Young male Sprague-Dawley rats were injected with a single dose of streptozotocin ([STZ] 65 mg/kg) to induce diabetes.
|
28297724 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mice with acute diabetes induced by STZ were administered metformin by gavage.
|
28439456 |
2017 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
T-cell composition, function, and insulitis levels were studied at Days 11 and 50 during diabetes development (i.e. post-first STZ injection).
|
28707492 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
The present study aimed to investigate resveratrol effects on catalase (CAT) and glutathione peroxidase (GPx) gene and protein expression, their phosphorylation states and activities in rat liver of STZ-induced diabetes.
|
24740756 |
2014 |