SIM2, SIM bHLH transcription factor 2, 6493

N. diseases: 69; N. variants: 4
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 Biomarker group BEFREE Together, these exciting new data support a role for SIM2s in promoting human breast tumor differentiation and maintaining epithelial integrity. 22777354 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group LHGDN To our knowledge, SIM2s is the first protein shown to bind and repress the SLUG promoter, providing a plausible explanation for the development role and breast tumor-suppressive activity of SIM2s. 18160708 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 Biomarker group BEFREE To our knowledge, SIM2s is the first protein shown to bind and repress the SLUG promoter, providing a plausible explanation for the development role and breast tumor-suppressive activity of SIM2s. 18160708 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group LHGDN These results suggest that SIM2s has breast tumor suppressive activity. 16840439 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group BEFREE These results suggest that SIM2s has breast tumor suppressive activity. 16840439 2007