SIX1, SIX homeobox 1, 6495

N. diseases: 200; N. variants: 12
Disease: Hydronephrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020295
Disease: Hydronephrosis
Hydronephrosis 		0.120 Biomarker disease BEFREE Furthermore a lack of Six1 gene in the ureter leads to hydroureter and hydronephrosis. 24899122 2014
CUI: C0020295
Disease: Hydronephrosis
Hydronephrosis 		0.120 Biomarker disease BEFREE A lack of Six1 in the ureter led to hydroureter and hydronephrosis without anatomical obstruction when kidney formation was rescued in Six1(-/-) embryos by specifically expressing Six1 in the metanephric mesenchyme, but not the ureter, under control of the Eya1 promoter. 20110314 2010
CUI: C0020295
Disease: Hydronephrosis
Hydronephrosis 		0.120 Biomarker disease HPO