SIX3, SIX homeobox 3, 6496

N. diseases: 117; N. variants: 14
Disease: Subfertility ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0729353
Disease: Subfertility
Subfertility 		0.010 Biomarker disease BEFREE We have studied 3 different homeodomain genes Otx2, Vax1, and Six3 and found that the deletion of one allele for any of these genes in mice produces subfertility or infertility in one or both sexes, despite the presence of one intact allele. 30261489 2019