SLC1A2, solute carrier family 1 member 2, 6506

N. diseases: 208; N. variants: 12
Disease: Liver Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.030 Biomarker disease BEFREE While the loss of EAAT-2 protein in ALF samples was post-translational in nature, EAAT-1 protein remained within normal limits. 24164438 2014
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.030 AlteredExpression disease BEFREE Loss of expression of GLT-1 results in increased extracellular brain glutamate in acute liver failure. 11746425 2001
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.030 AlteredExpression disease BEFREE Ammonia-induced reductions in expression of GLT-1 resulting in increased extracellular glutamate concentrations could explain some of the symptoms (hyperexcitability, cerebral edema) characteristic of hepatic encephalopathy in acute liver failure. 10555780 1999