SLC1A2, solute carrier family 1 member 2, 6506

N. diseases: 208; N. variants: 12
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 AlteredExpression disease BEFREE In this study, the effects of miR-124 on GLT-1 expression in astrocytes after ischemic stroke were explored using an in vitro model of ischemic stroke (oxygen-glucose deprivation/reperfusion, OGD/reperfusion). 31004734 2019
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 Biomarker disease BEFREE However, the role of orexin-A in the regulation of GLT-1 in ischemic stroke still remains unclear. 27837432 2017
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 AlteredExpression disease BEFREE Recent studies have uncovered that accumulation of glutamate after ischaemic stroke is closely associated with the down-regulation of glutamate transporter-1 (GLT-1) expression, suggesting that GLT-1 expression critically controls glutamate accumulation and the abnormal glutamate transport-elicited neuronal cell excitotoxicity in patients with ischaemic stroke. 24943094 2014