SLC2A4, solute carrier family 2 member 4, 6517

N. diseases: 158; N. variants: 7
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 Biomarker disease BEFREE CI = confidence interval; GLUT4 = glucose transporter 4; HOMA-IR = homeostatic model assessment for insulin resistance; HR = hazard ratio; LATS = Latin American Thyroid Society; MetS = metabolic syndrome; OR = odds ratio; ScH = subclinical hypothyroidism; T2DM = type 2 diabetes mellitus; T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating hormone. 30742573 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 Biomarker disease BEFREE We investigated the changes in the mRNA levels of the glucose transporter 4 (GLUT4) and found that MβCD application may lead to a significant improvement in glucose transport in ASC<sub>EMS</sub>. 29385746 2018
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 AlteredExpression disease BEFREE Drugs also increased GLUT4 and PPARγ protein expression compared with MS control group. 30256492 2018
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 GeneticVariation disease BEFREE Ameliorated TNF-α-induced inflammation and insulin resistance in adipocytes via activation of insulin signaling and enhanced GLUT4 translocation suggesting a reduced hyperglycemia associated with the metabolic syndrome. 28759152 2017