SLC2A5, solute carrier family 2 member 5, 6518

N. diseases: 48; N. variants: 2
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 Biomarker disease BEFREE To shine more light on the relationship between nanoparticle structure and cell uptake, we have designed several micelles based on fructose containing block copolymers, which are selective to GLUT5 receptors found on breast cancer cell lines. 30550258 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 Biomarker disease BEFREE GLUT5 (fructose) and GLUT2 (glucose/fructose) might provide alternative targets for BC imaging as to why effects of hypoxia on GLUT1/2/5 levels and function were examined in human BC models. 29913554 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 Biomarker disease BEFREE Fructose-specific facilitative hexose transporter GLUT5 represents an alternative biomarker for PET imaging of hexose metabolism in BC. 29142019 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 Biomarker disease BEFREE The high affinity of GLUT5 transporter for d-fructose in breast cancer cells has been discussed intensely. 28371343 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 Biomarker disease BEFREE Taken together these results are consistent with GLUT 5 not being essential for fructose uptake in breast cancer cells and tissues. 22073218 2011
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 Biomarker disease BEFREE Expression analysis of GLUT isoforms was performed on two GLUT5 expressing breast cancer cell lines using western blotting and immunocytochemistry. 19586773 2009
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 AlteredExpression disease BEFREE In situ RT-PCR and ultrastructural immunohistochemistry confirmed GLUT5 expression in breast cancer. 16523487 2006
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 Therapeutic disease CTD_human Therefore, it is of clinical interest to investigate whether AS against Glut5 mRNA can tackle breast cancer. 15449313 2004
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.380 AlteredExpression disease BEFREE Therefore, it is of clinical interest to investigate whether AS against Glut5 mRNA can tackle breast cancer. 15449313 2004