BMP4, bone morphogenetic protein 4, 652

N. diseases: 423; N. variants: 21
Disease: Agenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0000846
Disease: Agenesis
Agenesis 		0.040 GeneticVariation disease BEFREE After that, the coding exons of BMP4 were examined in 114 TA patients using Sanger sequencing. 31128441 2019
CUI: C0000846
Disease: Agenesis
Agenesis 		0.040 GeneticVariation disease BEFREE This case-control study was designed to evaluate the association of the polymorphism rs17563 in BMP4 gene with susceptibility of isolated human tooth agenesis in a Chinese Han population. 26166641 2015
CUI: C0000846
Disease: Agenesis
Agenesis 		0.040 GeneticVariation disease BEFREE As BMP4 is essential for the development of teeth and also for many other organs, it would be of considerable interest to find a BMP4 mutation that is associated only with tooth agenesis. 23841782 2013
CUI: C0000846
Disease: Agenesis
Agenesis 		0.040 GeneticVariation disease BEFREE These results indicate that polymorphisms in the TGFB3 gene and in BMP4 genes contribute to tooth agenesis. 22191848 2012