BMP4, bone morphogenetic protein 4, 652

N. diseases: 423; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.060 Biomarker disease BEFREE Additionally, interaction among BMP4 and cell matrix, tumor-vascular molecules and microglial immune cells also needs to be investigated, as this will enhance our knowledge about the role of BMP4 in human glioma and lead to the identification and/or development of novel therapeutic approaches that improve treatment outcomes of these devastating tumors. 28278424 2017
CUI: C0017638
Disease: Glioma
Glioma
0.060 Biomarker disease BEFREE Our study demonstrated that Fstl1 promoted glioma growth through the BMP4/Smad1/5/8 signaling pathway, and these findings suggest potential new glioblastoma treatment strategies. 29212066 2017
CUI: C0017638
Disease: Glioma
Glioma
0.060 Biomarker disease BEFREE Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence. 25808628 2016
CUI: C0017638
Disease: Glioma
Glioma
0.060 AlteredExpression disease BEFREE Interestingly, we found that the expression of BMP4 was significantly related to distant glioma metastasis. 24099560 2013
CUI: C0017638
Disease: Glioma
Glioma
0.060 Biomarker disease BEFREE Bone morphogenetic protein 4 inhibits cell proliferation and induces apoptosis in glioma stem cells. 21355779 2011
CUI: C0017638
Disease: Glioma
Glioma
0.060 Biomarker disease BEFREE BMP4 has a potential as a target for glioma therapy. 20730570 2010