BMP4, bone morphogenetic protein 4, 652

N. diseases: 423; N. variants: 21
Disease: Atrial Septal Defects ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018817
Disease: Atrial Septal Defects
Atrial Septal Defects 		0.020 Biomarker group BEFREE Jag1 and Bmp4 heterozygous null mice display ASD phenotypes in the adult, including TM hypoplasia and corneal adherence to the iris. 29452107 2018
CUI: C0018817
Disease: Atrial Septal Defects
Atrial Septal Defects 		0.020 GeneticVariation group BEFREE Heterozygous Bmp4 mutations in humans and mice cause severe ocular anterior segment dysgenesis (ASD). 29738572 2018