BMP4, bone morphogenetic protein 4, 652

N. diseases: 423; N. variants: 21
Disease: Cleft Palate-Lateral Synechia Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0795898
Disease: Cleft Palate-Lateral Synechia Syndrome
Cleft Palate-Lateral Synechia Syndrome 		0.210 Biomarker disease BEFREE Our studies demonstrate that aberrant BMP4-mediated signaling in CNC cells leads to mis-patterned facial skeleton and congenital bony syngnathia, and suggest an implication of mutations in BMP signaling pathway in human bony syngnathia. 24785830 2014
CUI: C0795898
Disease: Cleft Palate-Lateral Synechia Syndrome
Cleft Palate-Lateral Synechia Syndrome 		0.210 Biomarker disease MGD