SLC5A5, solute carrier family 5 member 5, 6528

N. diseases: 195; N. variants: 8
Disease: Adenoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 AlteredExpression group BEFREE In this study we evaluated the expression of CREB and NIS gene in thyroid non-functioning adenomas (n=18) and carcinomas (n=20), as well as in the corresponding normal tissue. 12720543 2003
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 AlteredExpression group BEFREE In all functioning thyroid nodules (toxic adenomas), a high expression of hNIS protein was detected with respect to normal surrounding tissue. 11788674 2002
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 Biomarker group BEFREE By immunohistochemistry, staining of hNIS protein was stronger in Graves' and toxic adenomas and reduced in thyroid carcinomas. 10576759 1999
CUI: C0001430
Disease: Adenoma
Adenoma 		0.040 AlteredExpression group BEFREE Increased NIS expression has been found in autonomous adenoma and Graves' disease, decreased levels of NIS protein and/or mRNA were observed in Hashimoto's disease, cold nodules, most thyroid cancers and cell lines derived therefrom. 9865544 1998