SLC6A2, solute carrier family 6 member 2, 6530

N. diseases: 238; N. variants: 24
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle
0.020 Biomarker disease BEFREE Netarsudil, an inhibitor of Rho kinase and a norepinephrine transporter, has been shown to lower elevated intraocular pressure (IOP) in controlled studies of patients with open-angle glaucoma and ocular hypertension, and in healthy volunteers. 29469601 2018
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle
0.020 Biomarker disease BEFREE To evaluate the efficacy and ocular and systemic safety of netarsudil 0.02% ophthalmic solution, a rho-kinase inhibitor and norepinephrine transporter inhibitor, in patients with open-angle glaucoma and ocular hypertension. 29199013 2018