SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 440; N. variants: 28
Disease: Heart valve disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018824
Disease: Heart valve disease
Heart valve disease 		0.010 Biomarker group BEFREE Although 5-HT1B receptors mediated the 5-HT-induced collagen secretion by human cardiac myofibroblasts, the contribution of this receptor type to valvulopathy was ruled out because double-KO mice deficient in both 5-HTT and 5-HT1B receptors showed the same cardiac alterations as 5-HTT-KO mice. 16380550 2006