SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 440; N. variants: 28
Disease: Somatization ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149779
Disease: Somatization
Somatization 		0.020 PosttranslationalModification disease BEFREE SLC6A4 methylation was further associated with the BSI-derived somatization dimension. 30201454 2019
CUI: C0149779
Disease: Somatization
Somatization 		0.020 Biomarker disease BEFREE Some results indicate that psychobiological aspects of depression and somatization overlap in part (e.g., the relevance of serotonergic pathways), but there is clearly more evidence for discrepancies of psychobiological pathways in depression and somatization (e.g., the relevance of proinflammatory immune processes; HPA-axis activity; monoamino acid availability; omega-3-concentration; the role of triallelic subtypes of 5-HTTLPR). 20403510 2010