SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 440; N. variants: 28
Disease: Psychiatric symptom ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233401
Disease: Psychiatric symptom
Psychiatric symptom 		0.020 GeneticVariation phenotype BEFREE There was no positive correlation between the 5-HTTLPR polymorphism and presence of mental symptoms in our sample, although the children were exposed to high levels of abuse, neglect, and urban violence. 25517418 2015
CUI: C0233401
Disease: Psychiatric symptom
Psychiatric symptom 		0.020 GeneticVariation phenotype BEFREE We believe that this set of findings argues for principled reversal of directionality in associations at the 5-HTTLPR locus and raises the possibility that allelic variation may have very different consequences for personality traits or psychiatric symptoms depending on epistasis or epigenetic context. 19361959 2009