|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We hypothesized that, consistent with the gene X environment (GXE) framework, an interaction between serotonin receptor (5-HTTLPR) gene and drug use would influence suicidal behaviors in BD patients.
|
31707246 |
2020 |
|
Suicidal
|
0.100 |
Biomarker
|
disease |
BEFREE |
Altogether, the baseline level and the changes in SLC6A4 mRNA expression during a MDE might predict the WSI and the occurrence of suicidal attempts and could be a useful biomarker in clinical practice.
|
29287766 |
2018 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Further research is necessary to understand how early life stress interacts with 5-HTT genotypes to confer risk for suicidal behavior through psychological mechanisms.
|
28890225 |
2017 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Significant interactions were observed between 5-HTTLPR genotype, SLEs and SSDs on both prevalence and incidence of suicidal ideation after adjustment for covariates.
|
24709017 |
2014 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The 5-HTTLPR short allele was associated with suicidal ideation 2 weeks after stroke, although the significance of this finding was not evident after adjustment.
|
23973249 |
2014 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
However, our linkage disequilibrium analyses indicated that there may be a greater risk for suicidal behavior in carriers of the S10 and L12 alleles of 5-HTTLPR.
|
20438360 |
2010 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Is the serotonin transporter polymorphism (5-HTTLPR) a potential marker for suicidal behavior in bipolar disorder patients?
|
20096463 |
2010 |
|
Suicidal
|
0.100 |
Biomarker
|
disease |
BEFREE |
To investigate whether genotypic variation of the serotonin transporter gene-linked promoter region (5-HTTLPR) moderates the effect of maltreatment on suicidal ideation in school-aged children.
|
19779024 |
2010 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Is the 5-HTTLPR polymorphism associated with bipolar disorder or with suicidal behavior of bipolar disorder patients?
|
17579356 |
2008 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In the present sample the triallelic 5-HTTLPR polymorphism (S, L(G), L(A)) was not associated with MAP-induced depressive disorder, MAP-induced psychotic disorder or suicidal behavior, but studies with larger sample sizes are warranted before excluding the role of the 5-HTTLPR polymorphisms in suicidal behavior among MAP abusers.
|
17875025 |
2007 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Childhood trauma interacts with low expressing 5-HTTLPR genotypes to increase the risk of suicidal behavior among patients with substance dependence.
|
17356577 |
2007 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our findings indicate the contribution of the SLC6A4 gene to susceptibility for suicidal behavior in women, but not in men.
|
17028448 |
2006 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
There seems to be an allelic association between the 5-HTTLPR S allele and suicidal behavior in alcohol-dependent subjects, but this relationship is restricted to male subjects.
|
15589566 |
2005 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Except for the possible heterogeneity between inpatients with a first episode of suicidal behavior and those with more than one, the 5-HTT gene was unlikely to be associated with suicidal behavior of psychotic patient in Han Chinese.
|
15531095 |
2004 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our results provide significant evidence supporting the association of the s allele of 5-HTTLPR polymorphism with suicidal behavior in the psychiatric population, also with violent suicide.
|
15121487 |
2004 |
|
Suicidal
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Thus, the genetically altered expression of the 5-HT transporter might be associated with more severe or violent suicidal behavior, but not with non-violent suicidal behavior.
|
12497618 |
2003 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This study suggests that the 5-HTTLPR polymorphism is unlikely to have major relevance to the pathogenesis of suicidal behavior in adolescence but may contribute to violent behavior in this population.
|
11353442 |
2001 |
|
Suicidal
|
0.100 |
Biomarker
|
disease |
BEFREE |
This suggests that a change in expression of the gene encoding the 5-HT transporter may be involved in violent suicidal behavior.
|
11326306 |
2001 |
|
Suicidal
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
From our results, this 5-HTTLPR polymorphism is unlikely to have a major effect on suicidal behavior in Chinese patients with schizophrenia.
|
11166082 |
2000 |