BMP7, bone morphogenetic protein 7, 655

N. diseases: 197; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.040 Biomarker disease BEFREE Mice with liver fibrosis received exogenous BMP7 intervention to observe improvement of liver fibrosis by using Masson's trichrome staining and detecting the expression of the HSC activation indicator alpha-smooth muscle actin (α-SMA) and the collagen formation associated protein type I collagen (Col I). 31435175 2019
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.040 AlteredExpression disease BEFREE DWYG demonstrates therapeutic potential to prevent liver fibrosis by modulating the balance between EMT and MET through reducing the expression ratio of TGF-β1/BMP-7 and inhibiting the excessive activation of Hh signaling pathway. 25345787 2014
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.040 Biomarker disease BEFREE Exogenous bone morphogenetic protein-7 reduces hepatic fibrosis in Schistosoma japonicum-infected mice via transforming growth factor-β/Smad signaling. 23539268 2013
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.040 AlteredExpression disease BEFREE Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats. 17127702 2007