BMP7, bone morphogenetic protein 7, 655

N. diseases: 197; N. variants: 3
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 Biomarker disease BEFREE There was a relatively higher level of BMP-7 and a lower level of gremlin expression in tumor tissues from patients with highly differentiated HCC when compared with poorly or moderately differentiated HCC (BMP-7, F=42.29, P<0.01; gremlin, F=37.93, P<0.01). 30008908 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 AlteredExpression disease BEFREE Consistent with these results, the expression of CTNND1 was positively correlated with β-catenin, WNT11, Cyclin D1, and BMP7 expression in human HCC specimens. 27193094 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 AlteredExpression disease BEFREE Taken together, these data suggest that KDM5C-mediated BMP7 inactivation is essential for HCC cell invasion. 26503415 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 Biomarker disease BEFREE These findings provide evidence that a high-expression level of BMP7 serves as a biomarker for poor prognosis for HCC. 23179403 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 Biomarker disease LHGDN Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling. 12478660 2003