SLC9A3, solute carrier family 9 member A3, 6550

N. diseases: 73; N. variants: 15
Disease: Central Diabetes Insipidus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0687720
Disease: Central Diabetes Insipidus
Central Diabetes Insipidus 		0.020 Biomarker disease BEFREE Furthermore, studies have shown that NHE3 is depleted at the apical surface of intestinal epithelial cells and downregulated in patients with CDI, but the role of DRA in CDI remains unknown. 29597352 2018
CUI: C0687720
Disease: Central Diabetes Insipidus
Central Diabetes Insipidus 		0.020 Biomarker disease BEFREE To confirm that inhibition of NHE3 was specific to C. difficile, human intestinal organoids (HIOs) were injected with C. difficile or healthy and CDI stool supernatant. 25552580 2015