SLC9A3, solute carrier family 9 member A3, 6550

N. diseases: 73; N. variants: 15
Disease: Obstructive azoospermia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4023106
Disease: Obstructive azoospermia
Obstructive azoospermia 		0.030 Biomarker disease BEFREE Instead, deficiency in solute carrier family 9 sodium/hydrogen exchanger isoform 3 (SLC9A3) may play a role by generating obstructive azoospermia and degraded epithelial structure in the reproductive tract. 30956978 2019
CUI: C4023106
Disease: Obstructive azoospermia
Obstructive azoospermia 		0.030 Biomarker disease BEFREE Loss of SLC9A3 decreases CFTR protein and causes obstructive azoospermia in mice. 30797621 2019
CUI: C4023106
Disease: Obstructive azoospermia
Obstructive azoospermia 		0.030 Biomarker disease BEFREE Furthermore, Slc9a3-/- mice developed obstructive azoospermia because of abnormal abundant secretions and calcification in the lumen of the reproductive tract. 28384194 2017