SLC10A1, solute carrier family 10 member 1, 6554

N. diseases: 54; N. variants: 7
Disease: Cholestasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.220 Biomarker disease BEFREE These findings suggested that NTCP deficiency may be a unique genetic factor causing transient cholestasis in early infancy, as well as, persistent hypercholanemia in pediatric patients. 30525015 2018
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.220 Therapeutic disease RGD Alisma orientale extract exerts the reversing cholestasis effect by activation of farnesoid X receptor. 29655695 2018
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.220 Therapeutic disease RGD Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats. 27090119 2017
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.220 AlteredExpression disease BEFREE The induction of hepatocellular injury induced by cholestasis was associated with a reduction in cytochrome P4503A4 (CYP3A4), CYP7A1, and UDP-glucuronosyltransferase 2B4 (UGT2B4) expression, as well as an increase in import (Na(+)-taurocholate co-transporting polypeptide, NTCP) system expression. 21526375 2011