SLC10A2, solute carrier family 10 member 2, 6555

N. diseases: 66; N. variants: 9
Disease: Hypercholesterolemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.030 Biomarker disease BEFREE However, decreasing cholesterol or BAs by partly inhibiting ASBT-mediated transport might be used for treatments of hypercholesterolemia, cholestasis and diabetes. 28336180 2017
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.030 Biomarker disease BEFREE Methyl 1-(3,4-dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) is a novel inhibitor of the ileal apical sodium-dependent bile acid transporter (ASBT/SLC10A2) developed for the treatment of hypercholesterolemia. 17470645 2007
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.030 Biomarker disease BEFREE Partial inhibition of ASBT may be useful in the treatment of hypercholesterolemia and intrahepatic cholestasis. 11396803 2001