|
Mycobacterium Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Therefore, we aimed to investigate the prevalence of several polymorphisms within innate immune response genes related to susceptibility to mycobacterial diseases (in SLC11A1, MBL2, TLR2, P2RX7, IL10, TNFA) in time series data from North and East Poland (1st-18th century AD, n = 207).
|
29763671 |
2018 |
|
Mycobacterium Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
The early identification in a mouse mutant susceptible to mycobacterial infection of the iron transporter Nramp1 allowed dissecting Nramp1 role in phagocytes, from the social amoeba <i>Dictyostelium</i> to macrophages.
|
29379774 |
2017 |
|
Mycobacterium Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Collectively, our results suggest an association of NRAMP1 3'-UTR and D543N polymorphisms with susceptibility to mycobacterial infection in Tunisian populations in relation to age and sex.
|
22609013 |
2012 |
|
Mycobacterium Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Although genetic variants in SLC11A1 (NRAMP1) have been associated with mycobacterial diseases, these findings have not been extensively validated in pulmonary Mycobacterium avium complex (MAC) infection.
|
22387151 |
2012 |
|
Mycobacterium Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
The natural resistance-associated macrophage protein 1 (NRAMP1) is implicated in the pathophysiology of mycobacterial infections.
|
12195379 |
2002 |
|
Mycobacterium Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
We review possible genetic host susceptibility factors for BU that are relevant in other mycobacterial diseases: natural resistance-associated macrophage protein-1 (NRAMP-1), HLA-DR, vitamin D3 receptor, mannose binding protein, interferon-gamma (IFN-gamma) receptor, tumour necrosis factor alpha (TNF-alpha), interleukin (IL)-1 alpha, 1 beta and their receptor antagonists; and IL-12.
|
11469950 |
2001 |
|
Mycobacterium Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Genetic and epidemiologic data were collected on an extended family from this community, and the evidence for linkage to NRAMP1, a candidate gene for susceptibility to mycobacterial diseases, was assessed.
|
10882571 |
2000 |
|
Mycobacterium Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The NRAMP1 (natural resistance associated macrophage protein 1) gene may influence human mycobacterial disease susceptibility based on studies with the murine homologue Nramp1.
|
9841838 |
1999 |
|
Mycobacterium Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Indeed, one of the murine genes (Nramp1) was identified for its role in controlling a range of intramacrophage pathogens, including leishmanial, salmonella and mycobacterial infections.
|
9504332 |
1998 |
|
Mycobacterium Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Indeed, one of the murine genes (Nramp1) was identified for its role in controlling a range of intramacrophage pathogens including leishmania, salmonella and mycobacterium infections.
|
9355125 |
1997 |