STK33, serine/threonine kinase 33, 65975

N. diseases: 43; N. variants: 6
Disease: Tumor Cell Invasion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.050 Biomarker phenotype BEFREE Enforced STK33 expression promoted PNET cell proliferation, migration, and invasion and tumour growth and inhibited cell apoptosis, whereas STK33 depletion exerted the opposite effects. 31261148 2020
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.050 Biomarker phenotype BEFREE The results demonstrated that inhibition of STK33 in SCLC cells suppressed the cell proliferation and invasion while induced cell apoptosis. 28895411 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.050 PosttranslationalModification phenotype BEFREE STK33 methylation was associated with lymph node metastasis (P<0.05), tumor invasion (P<0.05), distant metastases (P<0.01) and tumor stage (P<0.01). 29434919 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.050 Biomarker phenotype BEFREE Enforced expression of STK33 promoted gastric cancer cell proliferation, migration, and invasion <i>in vitro</i> and <i>in vivo</i>, whereas reduced STK33 did the opposite. 29367428 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.050 Biomarker phenotype BEFREE STK33 can promote cell migration and invasion and suppress p53 gene expression in the NL9980 and L9981 cells. 25662617 2015