MTMR9, myotubularin related protein 9, 66036

N. diseases: 5; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.130 GeneticVariation disease BEFREE Polymorphism of rs2293855 in gene MTMR9 has been associated with obesity and metabolic syndrome. 24937802 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.130 GeneticVariation disease BEFREE There is evidence that obesity and obesity-related phenotypes are associated with variations in several genes, including NEGR1, SEC16B, TMEM18, ETV5, GNPDA2, BDNF, MTCH2, SH2B1, FTO, MAF, MC4R, KCTD15, SCG3, MTMR9, TFAP2B, MSRA, LYPLAL1, GCKR and FADS1. 21796137 2011
CUI: C0028754
Disease: Obesity
Obesity 		0.130 GeneticVariation disease GWASDB Association of single-nucleotide polymorphisms in MTMR9 gene with obesity. 17855449 2007
CUI: C0028754
Disease: Obesity
Obesity 		0.130 GeneticVariation disease BEFREE Our data suggested that genetic variations in MTMR9 may confer a predisposition towards obesity and hypertension through regulation of hypothalamic neuropeptides. 17855449 2007
CUI: C0015382
Disease: Extraversion (Psychology)
Extraversion (Psychology) 		0.100 GeneticVariation phenotype GWASCAT Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. 27918536 2017
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.020 GeneticVariation disease BEFREE Polymorphism of rs2293855 in gene MTMR9 has been associated with obesity and metabolic syndrome. 24937802 2014
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.020 GeneticVariation disease BEFREE Our data suggest that genetic variations in the FTO, SCG3 and MTMR9 genes independently influence the risk of metabolic syndrome. 21796137 2011
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome 		0.010 GeneticVariation disease BEFREE The MTMR9 rs2293855 polymorphism is associated with glucose tolerance, insulin secretion, insulin sensitivity and increased risk of prediabetes. 24937802 2014
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.010 GeneticVariation group BEFREE Our data suggested that genetic variations in MTMR9 may confer a predisposition towards obesity and hypertension through regulation of hypothalamic neuropeptides. 17855449 2007