SMPD1, sphingomyelin phosphodiesterase 1, 6609

N. diseases: 247; N. variants: 130
Disease: Unipolar Depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.030 Biomarker disease BEFREE A number of functional acid sphingomyelinase inhibitors are clinically available and have been used for decades to treat major depression. 31835809 2019
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.030 Biomarker disease BEFREE Many antidepressants are functional inhibitors of the acid sphingomyelinase and were designed for systemic treatment of major depression. 29698625 2018
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.030 Biomarker disease BEFREE Alternative splicing of SMPD1 coding for acid sphingomyelinase in major depression. 27866044 2017