SMS, spermine synthase, 6611

N. diseases: 263; N. variants: 9
Disease: Lumbar hyperlordosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1184923
Disease: Lumbar hyperlordosis
Lumbar hyperlordosis 		0.030 GeneticVariation disease BEFREE There were no relationships between coronal deformity, thoracic kyphosis, or lumbar lordosis with SRS-22r scores. 31674249 2019
CUI: C1184923
Disease: Lumbar hyperlordosis
Lumbar hyperlordosis 		0.030 Biomarker disease BEFREE In the ASD group, Cumulative Illness Rating Scale (CIRS) correlated fair to ODI, COMI (0.441 ≥ r ≥ 0.383, P < 0.021) and to SRS-22-r (r = -0.335, P = 0.046), Mini Mental State Examination correlated fair to COMI (r = -0.352, P = 0.035), "Pelvic Incidence minus Lumbar Lordosis" correlated fair to ODI (r = 0.361, P = 0.031), BESTest correlated moderate to ODI and COMI (r ≤ -0.505; P ≤ 0.002), TCMS correlated fair to ODI (r = -0.356; P = 0.033). 28858190 2018
CUI: C1184923
Disease: Lumbar hyperlordosis
Lumbar hyperlordosis 		0.030 GeneticVariation disease BEFREE XPA showed strong correlation to sagittal spinopelvic parameters-PT, SVA, lumbar lordosis (LL), pelvic incidence (PI) minus LL-and to HRQoL scores-ODI, SF-36 PCS and SRS-22 activity and pain. 29330576 2018