Disease: Complete atrioventricular block ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151517
Disease: Complete atrioventricular block
Complete atrioventricular block 		0.020 AlteredExpression disease BEFREE Using independent and agnostic bioinformatics approaches, CD45<sup>+</sup>CD11c<sup>+</sup> and CD45<sup>+</sup>CD11c<sup>-</sup> human leukocytes flow sorted from the CHB hearts highly expressed type I IFN response genes inclusive of SIGLEC1. 30518570 2019
CUI: C0151517
Disease: Complete atrioventricular block
Complete atrioventricular block 		0.020 AlteredExpression disease BEFREE High expression of SIGLEC1 in pregnant women with autoantibodies against Ro/SS-A indicates an enhanced risk for CHB development, and these women may benefit especially from IFN-α directed therapy, for example with hydroxychloroquine. 28501799 2017