SNAP25, synaptosome associated protein 25, 6616

N. diseases: 283; N. variants: 15
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.020 Biomarker group BEFREE Insulin-induced glycogen synthesis was suppressed by SNAP-P.g. in HepG2 cells.Our results suggest that P.g. translocation from the oral cavity to the liver may contribute to the progress of diabetes mellitus by influencing hepatic glycogenesis. 23899607 2013
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.020 AlteredExpression group BEFREE Microarray gene chip analysis, confirmed by quantitative PCR, showed that gene expression was decreased in diabetes islets: syntaxin-1A (27 +/- 2% of control levels), SNAP-25 (31 +/- 7%), VAMP-2 (18 +/- 3%), nSec1 (27 +/- 5%), synaptotagmin V (24 +/- 2%), and synaptophysin (12 +/- 2%). 16443778 2006