SNCB, synuclein beta, 6620

N. diseases: 60; N. variants: 4
Disease: Fibrillation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0232197
Disease: Fibrillation
Fibrillation 		0.040 AlteredExpression disease BEFREE Whereas abnormal oligomerization and fibrillation of α-synuclein are now well recognized as initial steps in the development of synucleinopathies, β-synuclein is thought to be a natural α-synuclein anti-aggregant. 29370097 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation 		0.040 Biomarker disease BEFREE Vibrational Circular Dichroism Sheds New Light on the Competitive Effects of Crowding and β-Synuclein on the Fibrillation Process of α-Synuclein. 30239196 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation 		0.040 Biomarker disease BEFREE In this work, we compare fibril formation of αS and βS at pH 7.3 and mildly acidic pH 5.8, and we demonstrate that pH serves as an on/off switch for βS fibrillation. 28710275 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation 		0.040 Biomarker disease BEFREE Getting in charge of β-synuclein fibrillation. 28963338 2017