FSCN1, fascin actin-bundling protein 1, 6624

N. diseases: 175; N. variants: 5
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.030 AlteredExpression disease BEFREE The results survival analysis suggested high expression of fascin-1 protein in glioma patients with a shorter survival time. 30426092 2018
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease BEFREE Besides its traditional chemotherapeutic effect, TMZ can have four other targeted pathways: 1) slowed glioma cell growth; 2) inhibited glioma cell transmigration; 3) increased HLA-A2 and gBK tumor antigen production; 4) increased CTL-mediated cytolysis of the TMZ treated glioma cells due to the loss of their defensive membrane protrusions supported by fascin-1. 27359377 2016
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease LHGDN This is the first study to demonstrate a role for fascin in glioma cell morphology, motility, and invasiveness. 18283337 2008
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease BEFREE This is the first study to demonstrate a role for fascin in glioma cell morphology, motility, and invasiveness. 18283337 2008