BNIP3, BCL2 interacting protein 3, 664

N. diseases: 158; N. variants: 0
Disease: Glioblastoma Multiforme ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.030 Biomarker disease BEFREE These results suggest that Mcl-1 can block the ability of BNIP3 to induce cell death under hypoxia in GBM tumors. 26467103 2016
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.030 AlteredExpression disease BEFREE Furthermore, nuclear BNIP3 expression in GBM tumors correlates with decreased DR5 expression. 23579274 2013
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.030 AlteredExpression disease BEFREE Thus, nuclear BNIP3 may confer a survival advantage to glioma cells and explain, in part, why BNIP3 is expressed at high levels in solid tumors, especially GBM. 19339613 2009