SOD1, superoxide dismutase 1, 6647

N. diseases: 689; N. variants: 68
Disease: Prion Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.040 Biomarker group BEFREE Chronic neuroinflammation involves reactive microgliosis and astrogliosis, and is regarded as a common pathological hallmark of neurodegenerative diseases including Alzheimer's, Parkinson's, ALS and prion diseases. 31649496 2019
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.040 Biomarker group BEFREE Amyloid fibrils are pathological hallmarks of various human diseases, including Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS or motor neurone disease), and prion diseases. 30548150 2019
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.040 Biomarker group BEFREE Our data confirm the protective role of endogenous Sod1 in prion disease. 23349894 2013
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.040 Biomarker group BEFREE Thus, ALS has paralleled other neurodegenerative disorders, such as Alzheimer's and prion diseases, in which the inflammatory process is believed to participate directly in neuronal death. 11796754 2002