BNIP3L, BCL2 interacting protein 3 like, 665

N. diseases: 63; N. variants: 10
Disease: Parkinson Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.020 Biomarker disease BEFREE Our results demonstrate that Nix can serve as an alternative mediator of mitophagy to maintain mitochondrial turnover, identifying Nix as a promising target for neuroprotective treatment in PINK1/Parkin-related PD. 28281653 2017
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.020 Biomarker disease BEFREE These results indicate that Nix promotes cell death via interaction with POSH and activation of the JNK/c-Jun pathway and that Nix protein is induced and contributes to cell death in a cellular model of Parkinson disease. 17095503 2007