SOX9, SRY-box transcription factor 9, 6662

N. diseases: 466; N. variants: 25
Disease: Nodule ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028259
Disease: Nodule
Nodule 		0.030 AlteredExpression phenotype BEFREE Increase in dsDNA content (p < 0.0005), up-regulation of RUNX2, ALPL, SPP1 (p < 0.0005) and SOX9 (p < 0.005) gene expression, and more calcium nodule formation (p < 0.0005) were observed in d3D cultures in comparison to s3D ones over time. 31506241 2020
CUI: C0028259
Disease: Nodule
Nodule 		0.030 Biomarker phenotype BEFREE With Sox9, identical tumor morphology in terms of Edmondson grading and growth pattern did not infer the same degree of immunoexpression; and the largest tumor nodule was not representative of highest IHC score. 28764740 2017
CUI: C0028259
Disease: Nodule
Nodule 		0.030 Biomarker phenotype BEFREE In vitro, Sox9 nuclear export and calcific nodule formation is prevented by valve endothelial cells. 26634652 2016