SOX10, SRY-box transcription factor 10, 6663

N. diseases: 334; N. variants: 45
Disease: Schizophrenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 Biomarker disease PSYGENET These include NOS1, AKT1, DTNBP1, DNMT1, PPP3CC and SOX10, which have previously been associated with schizophrenia. 24399042 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 PosttranslationalModification disease BEFREE Several disease-associated changes in methylation have been reported: hypermethylation of SOX10 in schizophrenia, hypomethylation of HCG9 (HLA complex group 9) in bipolar disorder, hypermethylation of PRIMA1, hypermethylation of SLC6A4 (serotonin transporter) in bipolar disorder, and hypomethylation of ST6GALNAC1 in bipolar disorder. 24389572 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 Biomarker disease BEFREE These include NOS1, AKT1, DTNBP1, DNMT1, PPP3CC and SOX10, which have previously been associated with schizophrenia. 24399042 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 Biomarker disease PSYGENET In conclusion, the SOX10 rs139883 polymorphism influenced the age of onset of schizophrenia in a gender-specific manner and this may represent a vital genetic clue for the etiology of schizophrenia. 23456610 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 GeneticVariation disease BEFREE In conclusion, the SOX10 rs139883 polymorphism influenced the age of onset of schizophrenia in a gender-specific manner and this may represent a vital genetic clue for the etiology of schizophrenia. 23456610 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 PosttranslationalModification disease BEFREE In our present study we investigated methylation of genomic DNA and promoter methylation of Reelin and SOX10 genes in peripheral blood of twins suffering from schizophrenia. 23102571 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 GeneticVariation disease BEFREE The aim of this study was to evaluate the association between SOX10 rs139887 polymorphism and schizophrenia using an early onset sample in the Chinese Han population. 22640896 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 Biomarker disease PSYGENET The aim of this study was to evaluate the association between SOX10 rs139887 polymorphism and schizophrenia using an early onset sample in the Chinese Han population. 22640896 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 Biomarker disease PSYGENET In our present study we investigated methylation of genomic DNA and promoter methylation of Reelin and SOX10 genes in peripheral blood of twins suffering from schizophrenia. 23102571 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 Biomarker disease PSYGENET This study was conducted to clarify the exact role of SOX10 in the pathophysiology of schizophrenia. 17621166 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 Biomarker disease BEFREE This study was conducted to clarify the exact role of SOX10 in the pathophysiology of schizophrenia. 17621166 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 GeneticVariation disease BEFREE We concluded that genetic variations in the SOX10 gene do not contribute to susceptibility to Japanese schizophrenia. 16741945 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 PosttranslationalModification disease BEFREE Therefore, DNA methylation status of the SOX10 CpG island could be an epigenetic sign of oligodendrocyte dysfunction in schizophrenia. 15930386 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.380 PosttranslationalModification disease LHGDN Therefore, DNA methylation status of the SOX10 CpG island could be an epigenetic sign of oligodendrocyte dysfunction in schizophrenia. 15930386 2005