SOX10, SRY-box transcription factor 10, 6663

N. diseases: 334; N. variants: 45
Disease: Diffuse midline glioma, point mutation K27M in histone H3 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4289688
Disease: Diffuse midline glioma, point mutation K27M in histone H3
Diffuse midline glioma, point mutation K27M in histone H3 		0.010 GeneticVariation disease BEFREE Notably, SOX10, a key transcription factor associated with oligodendroglial differentiation and PDGFRA regulation, was up-regulated in both DCG and H3 K27M-mutant diffuse midline glioma, suggesting their developmental and biological commonality. 28852847 2017