SP4, Sp4 transcription factor, 6671

N. diseases: 30; N. variants: 16
Disease: Mental disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.020 GeneticVariation group BEFREE Sp4 hypomorphic mice could therefore serve as a genetic model to investigate impaired NMDA functions resulting from loss-of-function mutations of human SP4 gene in schizophrenia and/or other psychiatric disorders. 20634195 2010
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.020 GeneticVariation group BEFREE Reduced expression of the mouse Sp4 gene results in a variety of behavioral abnormalities relevant to human psychiatric disorders. 19401786 2009