Disease: Scleroderma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011644
Disease: Scleroderma
Scleroderma 		0.050 Biomarker disease BEFREE Attenuation of collagen production with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma. 16871529 2006
CUI: C0011644
Disease: Scleroderma
Scleroderma 		0.050 GeneticVariation disease BEFREE Moreover, a genetic polymorphism in SPARC has been associated with susceptibility to scleroderma. 15641096 2005
CUI: C0011644
Disease: Scleroderma
Scleroderma 		0.050 GeneticVariation disease BEFREE Single-nucleotide polymorphisms (SNPs) in the SPARC gene are reportedly linked to scleroderma in four ethnic groups: Choctaw Indians, Caucasians, African Americans and Mexican Americans. 15546965 2005
CUI: C0011644
Disease: Scleroderma
Scleroderma 		0.050 AlteredExpression disease BEFREE Association of novel polymorphisms with the expression of SPARC in normal fibroblasts and with susceptibility to scleroderma. 12428242 2002
CUI: C0011644
Disease: Scleroderma
Scleroderma 		0.050 Biomarker disease BEFREE The apparent overproduction of osteonectin by scleroderma fibroblasts is in accordance with the suggested activation of osteonectin expression during tissue remodeling. 2023219 1991