Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0457949
Disease: Chronic low back pain
Chronic low back pain
0.020 Biomarker disease BEFREE 7-9-month old wild-type and secreted protein acidic and rich in cysteine (SPARC)-null (a model of disc degeneration and LBP) male mice were treated with TAK-242 (TLR4 inhibitor) once, and following a 10-day washout, mice were treated 3 times/week for 8 weeks. 29908959 2018
CUI: C0457949
Disease: Chronic low back pain
Chronic low back pain
0.020 AlteredExpression disease BEFREE We tested the hypothesis that DNA methylation down-regulates SPARC expression in chronic LBP in pre-clinical models and in patients with chronic LBP. 21867537 2011