|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Identification of plasma secreted phosphoprotein 1 as a novel biomarker for upper tract urothelial carcinomas.
|
30844659 |
2019 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In specimens, the calcification occurred predominantly in well-differentiated carcinomas and the expression of the BMP2 and OPN elevated in calcified group.
|
29581780 |
2018 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
By immunohistochemistry, we analyse the association of Osteopontin variant expression in healthy breasts, hyperplasias, papillomas, and carcinomas in situ from 434 women to assess a) staining for OPN exon 4 (present in OPN-a and OPN-b) or OPN-c in low-risk to high-risk lesions b) correlations between staining and progression (DCIS with invasion, invasive cancer) or survival.
|
30353046 |
2018 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
OPN is overexpressed in several human carcinomas and has been implicated in inflammation, tumor progression, and metastasis.
|
28769537 |
2017 |
|
Carcinoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
BMP-2, OPN) that discriminated infiltrating carcinomas with microcalcifications from those without microcalcifications.
|
24758513 |
2014 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
However, the function and mechanism of OPN in renal carcinomas remain unknown.
|
19921477 |
2010 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Spp1 is an integrin-binding phosphoglycoprotein upregulated in carcinomas, and Mmps regulate tumour invasion.
|
17467979 |
2007 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The OPN expression was increased with the increasing Gleason scores of the carcinomas (Chi-square test, p < 0.001).
|
16331611 |
2006 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Osteopontin expression was higher in all the invasive carcinomas than in patient-matched normal mucosa.
|
16299231 |
2005 |
|
Carcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Immunohistochemical staining demonstrated osteopontin protein in intraluminal secretory material, necrotic debris, or stroma, and in histiocytes in all the Kossa-positive carcinomas and atypical cystic lobules.
|
11889596 |
2002 |
|
Carcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Despite its abundance in carcinomas, BSP expression was not detected in a panel of 11 human breast cancer cell lines (MCF-7, T47D, SK-Br-3, MDA-MB-453, MDA-MB-231, MDA-MB-436, BT549, MCF-7ADR, Hs578T, MDA-MB-435, and LCC15-MB) and OPN expression was detected only in two of these (MDA-MB-435 and LCC15-MB).
|
10418827 |
1999 |