SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Disease: Superficial ulcer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333307
Disease: Superficial ulcer
Superficial ulcer 		0.020 Biomarker disease BEFREE Silencing of OPN using lentiviral-OPN short hairpin RNA reduced the number of TRAP-positive osteoclasts and the extent of bone erosion in the AD-treated CIA mice. 29422077 2018
CUI: C0333307
Disease: Superficial ulcer
Superficial ulcer 		0.020 AlteredExpression disease BEFREE In contrast, lentiviral vectors expressing short hairpin RNA inhibited OPN expression and ameliorated articular swelling, cartilage erosion and monocyte infiltration in the ankle joints of CIA mice. 27851983 2017